I just installed the game on my machine. After putting the disk in the machine I got the same "This game is not compatible with your version of Windows...." the same message I got when installing the first two Draculas. So I used the same advice from the windows 7 thread that I used to install the Draculas, and the game appears to run fine.
I'm playing something else just now (Aura II) so I didn't continue with Necronomicon beyond the initial interview Stanton has with his friend, who gives him some pyramid-shaped object.
After I finish Aura II, I'll play through Necronomicon, and let everyone know how it runs.
Antoinetta